本发明提供一种包含颗粒的组合物，所述颗粒包含第一二价金属的碳酸盐种类和第二二价金属的碳酸盐种类； 其中所述颗粒是无定形的； 其中第一二价金属和第二二价金属处于+2的氧化态； 并且其中第一二价金属和第二二价金属各自独立地选自：Ca，Zn，Fe，Cu，Co，Ni，Mn，Mg和Cr。 本发明还提供了一种组合物，所述组合物包含二价金属碳酸盐和至少一种稳定剂，所述二价金属碳酸盐包含其任何衍生物，其中所述二价金属选自Zn，Cu，Co，Mn，Mg和Ni，任选特征在于BET为20-200m2/g。 还提供了包括所公开的颗粒组合物的药物或营养组合物。

A composition comprising a plurality of particles, each of said plurality of particles comprises a first divalent metal, a second divalent metal, and a carbonate specie ; said particle has a particle size of between 5 and 500 nm, and at least 70% by total weight of said carbonate specie is amorphous; wherein: any one of said first divalent metal and said second divalent metal is selected from the group comprising: Ca, Zn, Fe, Cu, Co, Ni, Mn, and Cr; and a molar ratio between said first divalent metal and said second divalent metal is between 10:0.05 and 1:1.