本发明提供了一种包含无定形碳酸钙(ACC)和稳定所述碳酸钙的无定形形式的磷酸化氨基酸和磷酸化肽至少之一的组合物。特别地,该肽可选自甲壳动物的蛋白质,所述蛋白质也由本发明提供,即GAP65、GAP22、GAP21和GAP12。本发明的组合物可用在药物制剂和营养制剂中。
由SEQ ID NO : 1所示的氨基酸序列组成的肽。本发明提供了一种包含无定形碳酸钙(ACC)和稳定所述碳酸钙的无定形形式的磷酸化氨基酸和磷酸化肽至少之一的组合物。特别地,该肽可选自甲壳动物的蛋白质,所述蛋白质也由本发明提供,即GAP65、GAP22、GAP21和GAP12。本发明的组合物可用在药物制剂和营养制剂中。
The present invention provides a composition comprising amorphous calcium carbonate (ACC) and stabilizing at least one of the amorphous forms of phosphorylated amino acids and phosphorylated peptides of the calcium carbonate. In particular, the peptide may be selected from a crustacean protein also provided by the invention, namely GAP65, GAP22, GAP21 and GAP12. The compositions of the present invention can be used in pharmaceutical preparations and nutritional preparations.
A peptide composed of an amino acid sequence as shown by SEQ ID NO: 1. The present invention provides a composition comprising amorphous calcium carbonate (ACC) and stabilizing at least one of the amorphous forms of phosphorylated amino acids and phosphorylated peptides of the calcium carbonate. In particular, the peptide may be selected from a crustacean protein also provided by the invention, namely GAP65, GAP22, GAP21 and GAP12. The compositions of the present invention can be used in pharmaceutical preparations and nutritional preparations.